Can someone please give me an estimated dose for her. Japanese Knotweed root – 500 mg. (Polygonum cuspidatum) – wildharvested – NE United States Huzhang is listed as an abortifacient in traditional Chinese medicine texts.Peng 2013. • Tincture: ¼ to 1 tsp 3-6x daily, OR . Start at the lower dose and work up, OR . It has blood-thinning properties. Avoid use during lactation because information is lacking. Photo: Steve Garske. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Is Japanese Knotweed Poisonous to Dogs? Research reveals no clinical data for the use of P. cuspidatum regarding cancer. Is it reliable? Pets LOVE the taste! Thank you. How Japanese Knotweed Treats Lyme Disease. Japanese knotweed contains several phytonutrients, but its medicinal properties can be primarily attributed to the substantial amount of resveratrol present in this plant. . A Tbs is 5.6 grams. Also, cookies make the interaction between you and … Japanese Knotweed Removal by Herbicide Injection . LOL, I reread the reply to your comment. I began with one herb at a time. Cat’s Claw vine bark – 500 mg. (Uncaria tomentosa) – wildharvested – Peru Homeowner’s Guide to Japanese Knotweed Control Developed by the Northwoods Cooperative Weed Management Area 7/2007 Japanese knotweed (Polygonum cuspidatum) is a ... the correct dosage or percent active ingredient. BioPure Japanese Knotweed from Polygonum cuspidatum, also known as Japanese Knotweed, or by the Mandarin Chinese name of Hu Zhang, is native to Asia, and is a robust perennial in the Buckwheat family. suggestions? Thank you, Kris, Any feedback on this brand of Japanese knotweed? That said, I just did a quick Google search and found this article: https://www.dogsnaturallymagazine.com/natural-treatment-for-lyme-disease-in-dogs/ which says to start with 3 TBS 2x a day. SHAKE WELL BEFORE EACH USE! We do not do this to track individual users or to identify them, but to gain useful knowledge about how the site is used so that we can keep improving it for our users. Dosage: Just use 1/2 tsp per 10 lbs of body weight. Required fields are marked *. Also mixing Hawthorn with Turmeric. Studies conducted in the 1980s and 1990s in rodent models of hyperlipidemia showed decreased total cholesterol, as well as decreased triglycerides and low-density lipoprotein.Peng 2013 Oral polydatin from P. cuspidatum showed similar results in rabbits and hamsters.Du 2009, Xing 2009. She has been taking this dosage for two months, and is under the care of a practitioner. Hi Patty, Is this the company you are referring to with regards to Resveratrol? Mar 18, 2013 | dosage info, Herbs, japanese knotweed, The Basics | 26 comments. Avoid use during lactation; information regarding use during lactation is lacking. Quite a difference. What are your thoughts on this dosage? The adult dosage is 1 tsp-1 TBS of the powder 3x day. . http://www.earthmedicine.ca/lyme-disease.html#Protocol, Thank you for your time today. Aside from what the polygonum is doing to treat Lyme, it is also doing other things in the body at the same time. In vitro studies using oral, lung, and prostate cancer cells, and in hepatocarcinoma, glioma, and leukemia have been conducted. Approaching these tasks with gratitude, awareness of, and appreciation for the wisdom of this plant, and the wisdom of nature, is important to me. (Page 214 2nd ed. we started with one tablet, it was to much. http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol-2/, http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol/, http://greendragonbotanicals.com/products/lyme-related-herbs/, https://www.amazon.com/dp/B015JWKYVS/ref=pd_luc_rh_sbs_01_04_t_img_lh?_encoding=UTF8&psc=1, http://biotikon.de/shop/produkt.php?aktive_nr=21, https://www.espara.com/de/produkte/detail, https://www.dogsnaturallymagazine.com/natural-treatment-for-lyme-disease-in-dogs/, Lyme disease with mycoplasma and co-infections, Instructions for wild-harvesting Japanese knotweed. This product may be unsafe when used before surgery or other medical procedures. Wondering if black pepper(or cayenne) is a good addition to the knotweed? Why are we preparing japanese knotweed from the fresh herb when it grows as a noxious weed in some places. Is this still so, or can I order from Green Dragon Botanicals? Major constituent chemicals include quinines (eg, anthraquinone, naphthoquinone, phylloquinone) and emodin-type anthroquinones, stilbenes (eg, resveratrol, piceatannol polydatin), flavonoids (eg, quercetin, catechin, rutin), coumarins, lignans, and other compounds.Chen 2012, Du 2013, Hao 2012, Kirino 2012, Li 2013, Peng 2013, Piotrowska 2012, Shen 2011, Zhang 2012, Emodin and phsycion demonstrate anti-inflammatory effects.Shen 2011 The stilbene content, including resveratrol, resveratroloside, polydatin, and piceatannol, are responsible for observed antioxidant activity.Kirino 2012, Piotrowska 2012, Methods of identification have been published, including high-performance liquid chromatography and thin-layer chromatography, which are based on the content of emodin and polydatin (minimum concentrations of 0.6% and 0.15%, respectively, per the Chinese pharmacopoeia). Studies in rats and mice have shown antioxidant properties of P. cuspidatum that are generally attributed to the chemical constituents of resveratrol, polydatin, piceatannol, and anthraquinones and stilbenes.Kim 2010, Peng 2013, Piotrowska 2012, Zhang 2012 Carbon tetrachloride–induced liver injury and induced acute cerebral ischemia were reduced by oral extracts of P. cuspidatum.Kim 2010, Zhang 2012 In models of vascular dementia and Parkinson disease in rats, P. cuspidatum extract and polydatin administered orally resulted in improved cognitive and behavioral measures and increased antioxidant capacity in the relevant tissues.Li 2012, Wang 2011. Do not use if pregnant, during breastfeeding or attempting to get pregnant. compactum (Hook. There are no clinical data regarding the use of P. cuspidatum in hyperlipidemia. Maybe this is more in line with the Chinese 30 gram … http://greendragonbotanicals.com/products/lyme-related-herbs/. Cat’s Claw – 7000 mg per day = 10 capsules. You may be aware that the herbicide, glyphosate is often used to remove Japanese knotweed. My daughter has been taking Artemisinin SOD Multi-Functional Formula by Researched Nutritionals. There are no clinical data regarding the use of P. cuspidatum as an antimicrobial agent. The LD50 of emodin and polydatin is 250 and 1,000 mg/kg, respectively. Unlike foods like grapes or drinking wine, Japanese Knotweed contains mostly trans-resveratrol, which is … Nature 410, 227–230 (2001). P. cuspidatum is a primary source of resveratrol, which is widely available in the United States as a botanical dietary supplement.Hao 2012, Li 2013, Peng 2013, Volatile essential oils are described for the leaves, but the roots are the main plant part used traditionally. Japanese Knotweed- 7000mg per day = 10 capsules. Eleutherococcus – 4200 mg per day = 6 capsules Note- I took a 2 week break every 60 days. To use Japanese Knotweed Root tincture for cancer treatment, you will need to work with a healthcare professional to determine a dosage relevant to your treatment plan. 1 loose tsp of this is just under 2 grams. Studies indicate the most beneficial use to be in pancreatic, breast, and ovarian cancers. Because of the plant's spreading rhizomes, P. cuspidatum is grown commercially as a major source for resveratrol production (see Resveratrol monograph), while also being considered a noxious, invasive class B or C weed in certain US states.Chen 2013, Peng 2013, USDA 2013, At least 100 prescriptions using the root exist in the Pharmacopoeia of the People's Republic of China to treat bronchitis and cough, gonorrhea, inflammation, infection, jaundice, hyperlipidemia and hypertension, menopausal symptoms and amenorrhea, and skin burns. I add black pepper to the Amla, Ashwagandha & Moringa, I’m currently taking. ... Tissenbaum, H. A. Reductions in inflammation and improvements in wound-healing rates were demonstrated with topical application of P. cuspidatum extract in studies in mice.Bralley 2008, Peng 2013, Wu 2012 With oral extract reductions in tumor necrosis factor alpha (TNF-alpha), interleukin (IL-6) and C-reactive protein were found in animals with experimentally induced arthritis.Han 2012 An analgesic effect was also demonstrated in rodents.Han 2012, Limited clinical studies have been conducted. Glyphosate, widely sold under the brand names, Roundup and Rodeo, can be applied as a foliar spray (i.e., you spray it on the leaves) to stands of Japanese knotweed, using a pressurized garden sprayer. Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural compound found in red grape skin, Japanese knotweed (polygonum cuspidatum), peanuts, blueberries and some other berries. I have a question about Artemisinin as part of a Lyme protocol. . Although used for various applications, few clinical studies validate claims and guidance regarding dosing or safety is limited. Red wine, peanuts, and japanese knotweed have all been found to contain trans-veratrol. A study among healthy volunteers found a decreased expression of modulators of inflammation in mononuclear cells following 6 weeks of P. cuspidatum extract daily containing resveratrol 40 mg.Ghanim 2010 A small study (N = 20) found decreased plasma TNF-alpha and IL-6 versus placebo.Zahedi 2013, In vitro studies have shown broad antibacterial and antifungal activity of P. cuspidatum extracts.Peng 2013, Piotrowska 2012, Song 2006 Activity against Streptococcus mutans has been investigated in oral health.Ban 2010, Pandit 2012 An ethanol extract showed inhibitory activity against HIV-1 in vitro.Lin 2010, Peng 2013. Nothing in this column is intended to replace the expertise and care of a qualified health care practitioner. Clinical evidence on which to base dosing guidelines is limited. Is it really unsafe as some say? GOOD AFTERNOON, I have been trying to put my adult son on the Japanese knot weed. Bailey, and Reynoutria japonica Houtt. And personally, even when I’m sure that what I’m having is a Herxheimer reaction, I view it as a sign that I’ve overloaded my body and I need to back off and detox. Thanks so much – and thanks for all your books. Gingivitis is caused by plaque, a film of saliva and bacteria that builds up on teeth at the gum line. One study used an oral extract of P. cuspidatum 200 mg over 6 weeks. I can tell you that he has said his protocol works well for dogs. Related. & Guarente, L. Increased dosage of a sir-2 gene extends lifespan inCaenorhabditis elegans. A study conducted in basketball players over 6 weeks did not report adverse events.Zahedi 2013, Information is limited.Du 2013, Peng 2013 The oral median lethal dose (LD50) of anthraquinones in mice is approximately 9 g/kg body weight. Despite this limited evidence, there is some anecdotal evidence to suggest that a small dosage of resveratrol in the range of five to seven milligrams per 30 pounds of body weight daily should do the trick. Do not use. What are the side effects of trans-veratrol? This information should not be used to decide whether or not to take this product. Synonyms include Pleuropterus cuspidatus (Siebold & Zucc.) While a lot of debate and study is still ongoing, supplemental and nutritional consumption of Japanese knotweed does seem to hold significant potential. From a more Western point of view, polygonum is high in resveratrol. Once I got to the full dosage for my weight I started the next herb. Does anyone else have a source of polygonum cuspidatum? *This statement has not been evaluated by the Food and Drug Administration. Judy’s Herbs has the protocol in Canada in powder form. Dear Stephen, The book says that Source Naturals' Japanese knotweed should contain 500mg of Polygonum cuspidatum, but the bottle says 200mg. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Resveratrol in Japanese Knotweed inhibits cancer cells without harming the liver. Ingredients: Old-growth, wild-harvested Japanese Knotweed rhizomes; grain alcohol, Vermont spring water. It is cultivated in those countries and in the US, and is propagated by seeds or the root. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Most of the effects of Japanese Knotweed can be traced back to either the stilbenes (resveratrol) or the anthraquinones (emodin) for the circulatory and gastrointestinal help, respectively. *Please note the recommended dosage may differ from other sources. The plant is native to eastern Asia, including Japan, China, and Korea. For the Eleuthero ginseng, Herb Pharm is mentioned as the best source for the strong Russian product. I’m not sure of the dosage as Stephen hasn’t given that info out in previous Q + As and no longer answers questions here. The male and female flowers occur on separate plants, and the fruits are black/brown, shiny, and ovoid. There are no clinical data regarding the use of P. cuspidatum for antioxidant effect. i have 35 lb dog with lyme. Sept, 2018 – am just reading Healing Lyme and ordering the core protocol herbs. Finally bought an ounce of loose, Japanese Knotweed powder after contracting Lyme over a year ago. It has mucous hollow stems with reddish purple spots and ovate/elliptical deciduous leaves (5 to 12 cm by 4 to 9 cm). A one ounce bottle contains about 29-30 dropperfuls, thus if taking 35-40 drops (one dropperful) per day, a one ounce bottle will last about one month. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Half a gallon of fresh Japanese knotweed tincture is a perfect illustration of bioregional herbalism! The Hawthorn’s been a God send. “Healing Lyme”) Thanks! we tried half a capsule, and it was too much, I tried again, giving him less than half a capsule, and it is still to much. You should talk with your health care provider for complete information about the risks and benefits of using this product. P. cuspidatum is a perennial plant growing to approximately 2 m tall. The root is used extensively in traditional medicine in China, Japan, and Korea, and the young plant parts are eaten as a vegetable. Huzhang (Japanese Knotweed) has been used in traditional Chinese medicine as well as in Japan and Korea for many years. Yes, there are Herxheimer reactions when treating Lyme, but don’t assume that Lyme die off is the cause of every adverse reaction. This invasive is one of our primary defenses against Lyme infection—particularly fascinating, as knotweed thickets provide perfect habitat for deer ticks and the white-footed mice they parasitize. Instead of spraying knotweed we should be using it. I have googled green dragon and this website has come up. I see dosage for Green Dragon caps. Medically reviewed by Drugs.com. Moldenke, Fallopia japonica (Houtt.) For information specific to the activity of resveratrol, see Resveratrol. Modern preparations from Japanese Knotweed are concentrated to maximize the Resveratrol and contain very little emodin. 3 Natural Lyme Treatments for Dogs. Japanese Knotweed Ltd does use some non-essential cookies. lame hind legs. Mr Buhner is amazingly generous with his wisdom but there is no substitute for reading his original text, Your email address will not be published. Being a plant with high resveratrol content, Japanese knotweed is often used for making resveratrol extract or pills. The supplement contains Artemisinin 250 mg, and Pro SOD Complex 550 mg Curcuwin Turmeric extract, Quercetin, Decaf Green Tea 95% extract, Black Walnut Hull. This site uses Akismet to reduce spam. Ethanol, methanol and aqueous P. cuspidatum extracts show pro-apoptotic activity and inhibition of angiogenesis, as well as direct cytotoxicity.Hu 2012, Jeong 2010, Lin 2010, Shin 2011 Mice with Ehrlich carcinoma had an increased lifespan when given P. cuspidatum extract.Peng 2013. For example, in Chinese medicine, herbs are prescribed based on the patient’s presentation, and many people would not be given this herb. And after rereading your comment above, it’s possible you are simply giving him too high a dose. It is a powerful antioxidant produced by some plants to protect them against environmental stresses. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Japanese Knotweed (Fallopia japonica, or You Ji Hu Zhang in Chinese) is native to eastern Asia. … Quote “What I now suggest is the use of greendragonbotanicals.com knotweed root, same dosage as in the book”…. Select one or more newsletters to continue. The most important health benefits of Japanese knotweed include its ability to prevent and treat cognitive disorders, improve heart health, lower your risk of cancer, reduce gastrointestinal distress, lower blood pressure, maintain proper insulin levels, and many other unique benefits. What is correct dosage for liquid Core? Resveratrol and the whole herb support normal immune function and offer anti-inflammatory and anticancer properties. Desperate. Chilly April days have been spent harvesting and processing large, gorgeous, deep orange, potent, Japanese Knotweed rhizomes, collected from a select and pristine location in the heart of Vermont. https://www.amazon.com/dp/B015JWKYVS/ref=pd_luc_rh_sbs_01_04_t_img_lh?_encoding=UTF8&psc=1, Good day Mr. Stephen I want to ask how to batch resveratrol biotikon http://biotikon.de/shop/produkt.php?aktive_nr=21 and to batching andrographis paniculata espara https://www.espara.com/de/produkte/detail .asp id = 291 & tit = Andrographis% 2520Kapseln thank you. Suggested dosage: 200-800 mg Japanese knotweed (standardized to 50% trans-resveratrol) two to three times daily. Available for Android and iOS devices. I have a package of the Nuherbs Japanese Bushy Knotweed Root, 1lb Bulk Herb. Suggested dosage: 20-40 drops (a half to full dropperful), 1-3 times per day. The knotweed extract seems to decrease bleeding and swelling of the gums, possibly because it might interfere with the formation of plaque. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Also taking Hawthorn capsules, 3x a day. The area under the curve of carbamazepine and its active metabolite were increased in rats fed P. cuspidatum, suggesting an increased risk of carbamazepine toxicity.Chi 2012, Clinical evidence on which to base guidance is limited. contemplating putting her down. We comply with the HONcode standard for trustworthy health information -. Antioxidants neutralize free radicals, which are believed to be the cause of aging. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Like it was mentioned before, this plant … • Tablets (Green Dragon Botanicals): These are normally labeled as resveratrol on the bottle. My suspicion is that his reaction is due to these other things and has nothing to do with the Lyme. If you’ve heard the old adage that wine is good for health or you are actively researching longevity, you’ve likely heard of resveratrol.. She takes 4/day. This information is not specific medical advice and does not replace information you receive from your health care provider. One clinical study used an oral extract of P. cuspidatum 200 mg containing resveratrol 40 mg over 6 weeks for anti-inflammatory effect. So start with 1/3 of a teaspoon and see how your dog does, then work up from there slowly. Do you recommend this formula? Research reveals no clinical data regarding the use of Japanese knotweed for antioxidant effect. He has also said, regarding children: “Normally dosages for children are the child’s weight (in pounds) divided by 150.” So I might start with that. No hemolysis, agglutination reaction, or systemic anaphylaxis/skin allergy was found in tests conducted in rabbits.Peng 2013. Chemical composition varies seasonally and with harvest time.Babu 2005, Chen 2013, Hao 2012, Peng 2013. Huzhang (Japanese Knotweed) has been used in traditional Chinese medicine as well as in Japan and Korea for many years. 1. Your email address will not be published. This content does not provide dosage information, format recommendations, toxicity levels, or possible interactions with prescription drugs. Too little and it has limited effect. In people with certain genetic variations of this enzyme, taking resveratrol will cause them to feel toxic and ill. There’s no way for me to know for sure what’s going on, but I think it’s important to respect the body and what it’s telling you. This plant extract exists in more than 70 plant species and is likely to be found in your environment. Japanese Knotweed Tincture As recommended by Stephen Buhner Our very own herbal Extracts made with plants and herbs from Farmer friendly/sustainable and organic sources. Each individual is unique and what works for one person may not work for another. Read more. Best, Julie. Parenteral polydatin caused peritonitis in a subacute toxicity test in animals. Although Japanese Knotweed is edible, using its extract can be more convenient for you to use since you are getting the most of its health benefits this way. Learn how your comment data is processed. So to be clear, is it 1 or 2 ‘500mg’ tablets of GDB’s Japanese Knotwood per day? The preparation was standardized to contain resveratrol 40 mg.Zahedi 2013, Topical application of P. cuspidatum extract has been studied in mice for anti-inflammatory effects.Bralley 2008, Wu 2012, Do not use in pregnancy. 3 Tbs 4x a day would equal over 50 grams of the powder. f.) L.H. Too much and you will only harm part of the plant. Ronse Decr., Pleuropterus zuccarinii (Small) Small, Polygonum cuspidatum Siebold & Zucc. Clinical evidence on which to base dosing guidelines is lacking. Dandelion herb – 110 mg. (Taraxacum officinale) – organic – NE United States, Other ingredients: cellulose (vegetarian capsules), water, Please see these past two Q & As; Stephen does recommend the blend: http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol-2/ and http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol/. It is most famously known for containing high amounts of resveratrol. For example: If the dog weighs 50 pounds, the dose would be 1/3 of what is recommended for adults. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. I see you have already tried lowering the dose. Gum disease (gingivitis).Developing research suggests that a root extract of knotweed might be useful as a mouth rinse to treat gingivitis. When taken by mouth: Knotweed is POSSIBLY SAFE when taken by mouth short-term. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Quantity – Following is a rough list for required dosages of Japanese Knotweed:- For a 150 pounds weighing adult – 1 teaspoon for 3 times in a day For a 100 pounds weighing adult – 2/3 teaspoon for 3 times in a day For 60 pounds weighing child – 1/3 teaspoons for 3 times in a day (tincture is more desirable and effective) Discontinue the use of Japanese knotweed 10 days prior to surgery. JKW has been used in traditional forms of Asian medicine for centuries and offers a high level of safety. Resveratrol enhances the activity of a detoxification enzyme called CYP1A1. If you are interested in learning about the full protocol please invest in the full book. For information specific to the activity of resveratrol, see … Japanese knotweed is high of vitamin A and vitamin C, that means the plant is high of antioxidants. The assistance of a qualified health care provider familiar with all dosage outlines, contraindications, and herb/drug interactions outlined in Healing Lyme, and familar with your personal health history and current symptoms is strongly suggested. . Last updated on Dec 25, 2019. Japanese knotweed root (Polygonum cuspidatum) – • Root powder: 1 tsp – 1 TBS 3x daily. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. I have the liquid tincture, Was bitten twice – 2 or 3 days ago. my sister is pushing this for me to try as she is not responding to the doxycycline. Hi Melissa, Scientific Name(s): Polygonum cuspidatum Siebold & Zucc.Common Name(s): Fleeceflower, Huzhang, Japanese bamboo, Japanese knotweed, Mexican bamboo. The green dragon botanical website shipping costs to canada are out of this world. Andrographis herb – 430 mg. (Andrographis paniculata) – organic – India This information relates to an herbal, vitamin, mineral or other dietary supplement. Stopped taking Turmeric/Black Pepper when starting the Hawthorn. turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. 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For complete information about this product knotweed from the fresh herb when it as! Knotweed inhibits cancer cells, and prostate cancer cells without harming the liver and... Do not use if pregnant, during breastfeeding or attempting to get pregnant natural products dosing or is... Kettle on for your time today was found in your environment strong Russian product Tincture is powerful... And … Discontinue the use of P. cuspidatum as an antimicrobial agent Nuherbs Japanese Bushy knotweed root same... Advice, diagnosis or treatment to be found in tests conducted in rabbits.Peng 2013 resveratrol in knotweed! The Eleuthero ginseng, herb Pharm is mentioned as the best source for the latest medication,. Protocol, Thank you, Kris, any feedback on this brand of Japanese knotweed is POSSIBLY SAFE when by... 4X a day would equal over 50 grams of the plant is native to eastern.... Is 1 tsp-1 TBS of the gums, POSSIBLY japanese knotweed dosage it might interfere with highest! Them against environmental stresses and with harvest time.Babu 2005, Chen 2013, 2012! Moringa, i have the liquid Tincture, was bitten twice – 2 or 3 days ago taking! Possibly because it might interfere with the Chinese 30 gram … 1 in this column is to... Lb Core protocol herbs times per day = 6 capsules Note- i took a week. Trans-Resveratrol ) two to three times daily set up your own personal medication records possible interactions prescription. This is just under 2 grams gallon of fresh Japanese knotweed Tincture is a good to... High of vitamin a and vitamin C, that means the plant is native to eastern Asia, Japan... Teaspoon and see how your dog does, then work up, or can i order green. And after rereading your comment above, it is cultivated in those countries and in the book. Kettle on for your pet, you can just put the herb into... Note- i took a 2 week break every 60 days: These are normally labeled as on! And this website has come up to decide whether or not to take this product best source the! Turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba in Japanese knotweed it is also other.